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What is the "last.fm" settings about ?
If enabled by the administrator of your AmpJuke installation, you can submit tracks streamed/played to last.fm.
This is done in the "last.fm" section in your personal settings, where you can set/change the following:
"Submit streamed tracks to last.fm": If checked (enabled), you can submit track details to your own last.fm profile. The tracks you listen to (stream) in AmpJuke will be sent to last.fm.
If you uncheck (disable) this setting, nothing will be sent to last.fm - this might be the case if you haven't got a last.fm profile and/or you don't want to submit streamed tracks to last.fm.
"last.fm username" and "last.fm password" will obviously be the username and password you use to login at the last.fm website.